The Lukesh lab uses synthetic organic chemistry in an effort to generate novel redox-active molecules with interesting biological properties. With a broad interest in molecular design and its application to biology and medicine, we are actively pursuing the following areas of research:

Medicinal Chemistry: Construction of novel selenium-containing scaffolds with useful redox properties and therapeutic applications.

Chemical Biology: Development of chemical tools for probing reactive sulfur and selenium species within a biological setting.

Synthetic Methodology Development: New methods involving electrophilic selenium catalysis for accessing privileged heterocyclic scaffolds via key C–C bond forming reactions.

Students participating in this research are exposed to a wide variety of topics and techniques at the ever-widening interface of chemistry and biology.